Monkeypox (MPX)

Click here to sign up for Maryland's MPX vaccine pre-registration.

Looking for updates about the local Monkeypox response? Text Monkeypox to 888777.

  1. Background
  2. Data on Cases
  3. Signs and Symptoms
  4. Transmission
  5. Prevention
  6. Testing & Treatment
  7. Resources


Human monkeypox is a rare but serious illness caused by infection with the monkeypox virus, which can infect humans and other animals, such as monkeys and rodents. The human monkeypox virus belongs to the genus Orthopoxvirus. The Orthopoxvirus genus also includes variola virus (which causes smallpox), vaccinia virus (used in the smallpox vaccine), and cowpox virus.

In May 2022, several clusters of human monkeypox cases were reported in countries that don't normally report human monkeypox, including the United States. People with monkeypox in the current outbreak generally report having close, sustained physical contact with other people who have monkeypox. Anyone who has been in close contact with someone who has monkeypox is at risk, regardless of gender or sexual orientation. Early data suggest that gay, bisexual, and other men who have sex with men make up a high number of cases. 

CDC is urging healthcare providers in the United States to be alert for patients who have rash illnesses  consistent with monkeypox, regardless of whether they have travel or specific risk factors for monkeypox and regardless of gender or sexual orientation.

CDC is working with state and local health officials to identify people who may have been in contact with individuals who have tested positive for monkeypox, so they can monitor their health.

On June 16, 2022, MDH reported a presumed human monkeypox virus infection in a Maryland resident.

Frequently Asked Questions

Am I at risk for Monkeypox (MPX)?

At this time, the risk to the general public appears to be low.  During the current global monkeypox outbreak, transmission is primarily through prolonged, close, physical, intimate contact with someone who has MPX. There have not been any MPX cases identified among healthcare providers evaluating and treating patients with MPX, or people who have had casual exposure to someone with monkeypox like sitting next to them on an airplane. Anyone who has been in close, physical, contact with someone who has MPX is at risk, regardless of gender or sexual orientation. Fact Sheet: Social Gatherings, Safer Sex, and Monkeypox

What should I do if I think I have Monkeypox (MPX)?

If you have a new or unexplained rash or sores, especially after having fever, headache, or swollen lymph nodes, or if you have had close, physical, intimate contact with someone who has been diagnosed with MPX, contact your healthcare provider immediately.

Can I get the Monkeypox vaccine?

People who are interested in getting the MPX vaccine should pre-register with the Maryland Department of Health system. The Frederick County Health Department will contact individuals on that list to offer appointments as clinics are scheduled. If you have trouble registering, call 443-488-4648 from 8:00am-4:30pm on Monday through Friday (excluding state holidays).

More frequently asked questions

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