We are updating webpages with the term "mpox" to reduce stigma and other issues associated with prior terminology. This change is aligned with the recent World Health Organization decision.

If you are interested in receiving the mpox vaccination, please call 301-600-3342 to make an appointment.


Human Mpox is a rare but serious illness caused by infection with the Mpox virus, which can infect humans and other animals, such as monkeys and rodents. The human Mpox virus belongs to the genus Orthopoxvirus. The Orthopoxvirus genus also includes variola virus (which causes smallpox), vaccinia virus (used in the smallpox vaccine), and cowpox virus.

In May 2022, several clusters of Mpox cases were reported in countries that don't normally report human Mpox, including the United States. People with Mpox in the current outbreak generally report having close, sustained physical contact with other people who have monkeypox. Anyone who has been in close contact with someone who has Mpox is at risk, regardless of gender or sexual orientation. Early data suggest that gay, bisexual, and other men who have sex with men make up a high number of cases. 

CDC is urging healthcare providers in the United States to be alert for patients who have rash illnesses  consistent with Mpox, regardless of whether they have travel or specific risk factors for Mpox and regardless of gender or sexual orientation.

CDC is working with state and local health officials to identify people who may have been in contact with individuals who have tested positive for Mpox, so they can monitor their health.

On June 16, 2022, MDH reported a presumed human Mpox virus infection in a Maryland resident.

Frequently Asked Questions

Am I at risk for Mpox?

At this time, the risk to the general public appears to be low.  During the current global Mpox outbreak, transmission is primarily through prolonged, close, physical, intimate contact with someone who has Mpox. There have not been any Mpox cases identified among healthcare providers evaluating and treating patients with Mpox, or people who have had casual exposure to someone with Mpox like sitting next to them on an airplane. Anyone who has been in close, physical, contact with someone who has Mpox is at risk, regardless of gender or sexual orientation. Fact Sheet: Social Gatherings, Safer Sex, and Monkeypox

What should I do if I think I have Mpox?

If you have a new or unexplained rash or sores, especially after having fever, headache, or swollen lymph nodes, or if you have had close, physical, intimate contact with someone who has been diagnosed with Mpox, contact your healthcare provider immediately.

Can I get the Mpox vaccine?

People who are interested in getting the Mpox vaccine should pre-register with the Maryland Department of Health system. The Frederick County Health Department will contact individuals on that list to offer appointments as clinics are scheduled. If you have trouble registering, call 443-488-4648 from 8:00am-4:30pm on Monday through Friday (excluding state holidays).

More frequently asked questions

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